Clinical Genomics

Dr. Yann Renaud, PhD

Computational biologist with 14 years in epigenetic-age research; architect of the biological-age model powering every Smart Santé report.

Dr. Yann Renaud, PhD

Dr. Renaud completed his doctorate in computational biology at EPFL in Lausanne, then spent four years as a postdoctoral researcher at the Karolinska Institutet, where he studied the epigenetic clocks that predict biological age from DNA methylation patterns. His work has been cited in over 60 peer-reviewed papers across longevity, oncology, and metabolic disease.

He joined Smart Santé to apply precision genomics in a clinical setting where the insights actually reach patients. He oversees the biological-age score that anchors every longevity report, refines the reference-range models quarterly, and holds the science team to a strict evidentiary standard: no claim ships without data to back it.

Dr. Renaud believes that the most important number in a longevity assessment is not a marker value but the gap between chronological and biological age — and that closing that gap is a tractable engineering problem, not a matter of luck.

Areas of Expertise

  • Epigenetic Age Clocks (Horvath, DunedinPACE)
  • Polygenic Risk Scoring
  • DNA Methylation Analysis
  • Telomere Biology
  • Biological Age Modelling

Education & Credentials

  • BSc Biochemistry — Université de Montréal
  • PhD Computational Biology — EPFL, Lausanne
  • Postdoctoral Fellow — Karolinska Institutet, Stockholm
  • BSc Biochemistry, Université de Montréal
  • PhD Computational Biology, EPFL (Lausanne)
  • Postdoctoral Research, Karolinska Institutet — Epigenetics of Ageing

Languages Spoken

French (native), English (fluent), Arabic (conversational)

A Note From Dr. Yann Renaud, PhD

"The most important number in a longevity assessment is not a marker value — it is the gap between your chronological and biological age. That gap is closable."
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